NanoBios Lab

IIT Bombay

Dr. Rohit Srivastava

Professor

I am currently working as a Professor at the Indian Institute of Technology, Bombay since September 2005. I completed my Bachelor of Engineering in Electronics Engineering from VNIT Nagpur in 1999 with distinction and was the recipient of scholarship of merit for graduating students for the year. I joined Tata Consultancy Services, SEEPZ, Mumbai for a short duration of a year. Not finding satisfaction in what I was doing, he decided to complete higher studies in the US. I subsequently went on to finish a Master of Science and a PhD in Biomedical Engineering from Louisiana Tech University, Ruston, LA, USA for which I received the "Best Student of the Year" award in 2005. My specialization lies in Biomedical Microsystems devices (MEMS) and nanoengineered biosensors. Read More

I am currently working as a Professor at the Indian Institute of Technology, Bombay since September 2005. I completed my Bachelor of Engineering in Electronics Engineering from VNIT Nagpur in 1999 with distinction and was the recipient of scholarship of merit for graduating students for the year. I joined Tata Consultancy Services, SEEPZ, Mumbai for a short duration of a year. Not finding satisfaction in what I was doing, he decided to complete higher studies in the US. I subsequently went on to finish a Master of Science and a PhD in Biomedical Engineering from Louisiana Tech University, Ruston, LA, USA for which I received the "Best Student of the Year" award in 2005. My specialization lies in Biomedical Microsystems devices (MEMS) and nanoengineered biosensors.
I have received the prestigious INAE Young Engineer Award 2010. I am also the recipient of the prestigious DBT-IYBA 2009 award. I have also been elected a Member of the National Academy of Sciences, 2011. Further, I have been awarded the Young Investigator awards from IIT Bombay (2010), DAE (2006) and DST (2006) and is also the recipient of technical awards from Intellectual Ventures Asia Pte Ltd. Six of my current projects have been submitted as patent applications to the US and Indian Patent Office. In a short duration of seven years at IIT Bombay, my team already published in over 35 international journals and I have also been awarded the prestigious BOYSCAST Fellowship from DST. My lab is focusing on developing technologies that can be commercialized and brought to use for the common man in India.

Dr. Vinay Saini

Senior Project Research Scientist

I have been working on TB Therapeutics, TB Diagnostics and malnutrition. In TB Therapeutics Project (India Health Fund, TATA TRUST), team members are trying to develop formulations against MDR TB while in TB Diagnostics project (IMPRINT INDIA), we are working on low cost, affordable TB diagnostics in co-ordination with ICMR labs, Pharma and Biotech companies, TB hospital, RNTCP Lab, European and US organizations. In other areas, I have been working on assessment of child malnutrition and development of patient friendly formulations against malnutrition. Recently, I have started my own start up for promoting translational research in Pharma and Biotech sector. I am open to collaborate with Pharma, Biotech industries and research organizations for R & D projects under an MOU.

Read More

I was engaged in formulation development and its characterization against infectious diseases. I developed and characterized novel vaccine delivery systems (microparticles) for infectious diseases (Hepatitis B & Filariasis). I developed and characterized (in-vitro) of non-viral gene delivery system for the delivery of siRNA, Plasmid DNA and minicircle DNA I got the expertise of teaching B. Pharm and M. Pharm students. During project supervision to M.Pharm dissertation students, I worked on nanoparticles, in situ gel and transdermal drug delivery system for the delivery of anti-cancerous, antibiotics and anti-allergic drugs.
Scientific Focus Areas:
ļ¶Formulation Development (Novel Vaccine/Drug/Gene Delivery System): Microspheres, Nanoparticles, Polyion Complex Micelles, Hydrogels, Transdermal Drug Delivery system, and Polymeric lamellar substrate particles of biodegradable polymers of lactides and glycolodes viz. L-PLA, DL-PLA, PLGA (50:50), PLGA (75:25).
In vitro characterization: Particle-size, polydispersity-index, zeta-potential (using Dynamic light scattering=DLS), adsorption/encapsulation efficiency (FTIR), in vitro release profile, stability studies (SDS-PAGE), HPLC, immunoblotting techniques, apoptosis assay (FACS) and cell line studies.
In vivo characterization: Immunological: Cell culture (splenocytes, lymphocytes and macrophages), Humoral (Indirect ELISA- IgM, IgG, IgE) and Cell Mediated Immune Assays (Sandwich ELISA- cytokines-IFN-gamma, IL-2, TNF-alpha), Lymphocyte transformation test, nitric-oxide assay.
Publications:
Vinay Saini, M.K. Sahoo, P.K. Murthy, Dharmveer Kohli. 2009. Polymeric lamellar substrate particles as carrier adjuvant for recombinant hepatitis B surface antigen. Vaccine [27 (2372–2378)].
Vinay Saini, Vikas Jain, M. S. Sudheesh, Saurabh Dixit, R. L. Gaur, M. K. Sahoo, S. K. Joseph, S. K. Verma, K. S. Jaganathan, P. K. Murthy, Dharmveer Kohli. 2010. Humoral and cell mediated immune responses after administration of a single shot Hepatitis B Vaccine formulated with PLA Microspheres. Journal of Drug Targeting [18 (3) 212-222].
Vinay Saini, Vikas Jain, M.S. Sudheesh, K.S. Jaganathan, P.K. Murthy, D.V. Kohli. 2011. Comparison of humoral and cell-mediated immune responses to cationic PLGA microspheres containing recombinant hepatitis B antigen. International Journal of Pharmaceutics [408 (50–57)].
Vinay Saini, Shiv K. Verma, Malaya K. Sahoo, Dharm V. Kohli, P. Kalpana Murthy. 2011. Sufficiency of a single administration of filarial antigens adsorbed on polymeric lamellar substrate particles of poly (l-lactide) for immunization. International Journal of Pharmaceutics 420 101–110.
Aakanchha Jain, Vinay Saini and Dharm Veer Kohli. Edible Transgenic Plant Vaccines For Different Diseases. 2013. Current Pharmaceutical Biotechnology [14 (5) 2013].
Vinay Saini, Shiv Kumar Verma, , P. Kalpana Murthy, Dharmveer Kohli. 2013. Poly(d,l)-lactide-co- glycolide (PLGA) microspheres as immunoadjuvant for Brugia malayi antigens.Vaccine [31 (38) : 4183-91].
Vinay Saini, Atul Kumar Verma, Vikas Kushwaha, Sujith Kurian Joseph, P. Kalpna Murthy, Dharmveer Kohli. 2013. Humoral and cell mediated immune responses elicited by Poly (DL-lactide) adjuvanted filarial antigen molecules. Drug Delivery [21(3):233-41].
Rekha Khaira, Jyoti Sharma, and Vinay Saini. 2014. Development and characterization of nanoparticles for the Delivery of Gemcitabine hydrochloride. (The Scientific World Journal, Article ID 560962).
Avinash Sharma, Jyoti Sharma, and Vinay Saini. 2014. Development and characterization of in situ oral gel of Spiramycin (BioMed Research International, accepted on 24 May, 2014: early online).
Conferences:
How to play safe in lab (October, 2013: ETH, Switzerland)
MIP-TEC, Basel, Switzerland (24 September, 2013)
5th Semmering Vaccine Symposium, Baden, Vienna (28-30 April, 2011)
60th Indian Pharmaceutical Congress (Diamond Jubilee, 2008, New-Delhi)
59th Indian Pharmaceutical Congress (2007, Banaras Hindu University, Varansi U.P.-India)
Awards:
Swiss Government Scholarship: 2013
Distinguished National Service Scheme (NSS) Camp Co-ordinator Award: December, 2012
Vienna Vaccine Stipend: 2011
Young Scientist Award: 2010
Best Research Paper Award: 2008 (Biotechnology and Biotherapeutics session), Indian Pharmaceutical Congress (60th IPC, New-Delhi).

Vivek Borse

PhD

After completing M. Tech I have joined as Senior Research Fellow (SRF) in the Dept. of Biosciences and Bioengineering under Prof. Rohit Srivastava at IIT Bombay. I got admission for PhD course in 2013; currently I am working on the project entitled “Development of nanodiagnostic method or device for the diagnosis of implant related orthopaedic infections”. My primary career focus is to perform research in an interdisciplinary field of nanotechnology, biotechnology and pharmacy providing pertinent solutions to healthcare. I would like to work in areas like nanobiotechnology, bionanosensors, nanodiagnostics, preformulation and formulation development, drug delivery, fermentation technology, downstream processing. Read More

After completing M. Tech I have joined as Senior Research Fellow (SRF) in the Dept. of Biosciences and Bioengineering under Prof. Rohit Srivastava at IIT Bombay. I got admission for PhD course in 2013; currently I am working on the project entitled “Development of nanodiagnostic method or device for the diagnosis of implant related orthopaedic infections”. My primary career focus is to perform research in an interdisciplinary field of nanotechnology, biotechnology and pharmacy providing pertinent solutions to healthcare. I would like to work in areas like nanobiotechnology, bionanosensors, nanodiagnostics, preformulation and formulation development, drug delivery, fermentation technology, downstream processing.
I have completed matriculation (in 2004) standing 3rd in school, intermediate (10+2) (in 2006) with distinction. Subsequently, I got admitted to R. C. Patel Institute of Pharmaceutical Education and Research for pursuing Bachelors of Pharmacy. I got 83.38 % in the B. Pharm and secured 1st rank in university throughout the total eight semesters of graduation and awarded with Gold Medal from North Maharashtra University, Jalgaon for the academic excellence in graduation (2010). I have also qualified GATE 2009 in Pharmaceutical, GPAT 2010 (conducted by M.S. University Baroda), NIPER-JEE 2010 (conducted by National Institute of Pharmaceutical Education & Research). After completing my graduation, I joined the Department of Pharmaceutical Technology (Biotechnology) for pursuing the Master’s programme [M. Tech (Pharm)] at NIPER, Mohali. During postgraduate tenure, I have qualified GATE 2011 in Biotechnology (conducted by IIT-Madras), I also qualified DBT BET JRF in Category A list. I have also qualified CSIR/UGC-NET June 2012 Eligibility for Lectureship. I have completed M. Tech (Pharm) successfully with cGPA of 9.18. In my dissertation work entitled, “Microbial synthesis of platinum nanoparticles and evaluation of their anticancer activity”, I have performed lot of experimental work to synthesize the different metallic nanoparticles and optimized different parameter for the synthesis of metal NPs and also performed cell line study to evaluate the anticancer potential of these NPs.

Sisini Sasidharan

PhD

I did my BDS from Govt. Dental College, Calicut and MTech in Nanomedical Science from Amrita Centre for Nanosciences and Molecular Medicine. I am pursuing my PhD in Multifunctional Theragnostic Agents for Cancer

Deepak Singh Chauhan

M.Sc-PhD

I completed my graduation in life science from University of Allahabad and post graduation in Biotechnology from IIT Bombay. Thereafter I joined PhD in Biomedical engineering under the guidance of Prof. Rohit Srivastava. Currently my research area is Hybrid organic-inorganic nanoparticles for the treatment of cancer. These particles are being used in lab for the photothermal therapy of breast cancer cells. Read More

Mukesh Kumar Kumawat

MTech-PhD

I'm pursuing MTech-PhD dual degree program. I'm working on graphene based material for cancer therapy. Hobbies: Fine art, swimming,athletics and playing TT. Read More

I'm pursuing MTech-PhD dual degree program. I'm working on graphene based material for cancer therapy. Hobbies: Fine art, swimming,athletics and playing TT.
Awards:
1. CSIR-UGC JRF December 2007
2. GATE 2008
3. CSIR JRF June 2010
4. GATE 2010

Nishant Kumar Jain

PhD

My name is Nishant Kumar Jain. I have completed my bachelors in pharmacy from shri Vishnu College of pharmacy in 2010. I have qualified GPAT, NIPER-JEE (AIR-79), MANIPAL-OET (AIR-55) as well as BITS. I have opted for Pharmaceutics branch in NIPER-Hyderabad to pursue my postgraduation. During my Postgraduate studies I got the glimpse of research work going on in the field of Nanotechnology. The learning experience I obtained during masters in “NIPER- Hyderabad” and project work in “IICT-Hyderabad” which is “learning by doing” helped me develop the skills which I consider will be very much useful for my future. I have been an ardent admirer of the educational system in IIT’S and always dreaming of being a part of it. Finally, I got admission in Ph.D Program in I.I.T Bombay through DST-INSPIRE Fellowship in 2013. I have a sound knowledge in the fundamentals of Development of Novel Drug Delivery System. The area of research that I am interested in is “Development of Targeted Polymeric & Lipid Based Nano Particulate Drug Delivery Systems” and “Bio-conjugation”. My Hobbies mainly include playing games like Baddy, Table Tennis and Cricket. Read More

My name is Nishant Kumar Jain. I have completed my bachelors in pharmacy from shri Vishnu College of pharmacy in 2010. I have qualified GPAT, NIPER-JEE (AIR-79), MANIPAL-OET (AIR-55) as well as BITS. I have opted for Pharmaceutics branch in NIPER-Hyderabad to pursue my postgraduation. During my Postgraduate studies I got the glimpse of research work going on in the field of Nanotechnology. The learning experience I obtained during masters in “NIPER- Hyderabad” and project work in “IICT-Hyderabad” which is “learning by doing” helped me develop the skills which I consider will be very much useful for my future. I have been an ardent admirer of the educational system in IIT’S and always dreaming of being a part of it. Finally, I got admission in Ph.D Program in I.I.T Bombay through DST-INSPIRE Fellowship in 2013. I have a sound knowledge in the fundamentals of Development of Novel Drug Delivery System. The area of research that I am interested in is “Development of Targeted Polymeric & Lipid Based Nano Particulate Drug Delivery Systems” and “Bio-conjugation”. My Hobbies mainly include playing games like Baddy, Table Tennis and Cricket.
Publications:
Synthesis and Antimicrobial Properties of TiO2 and TiO2: Cu Thin Films Synthesised by a Cost Effective Sol–Gel Process.Advanced Science, Engineering and Medicine, Vol. 4, pp. 279–287, 2012.

Professional Experience:
Worked as a project trainee for 1yr under the guidance of Dr.S.Ramakrishna, Principal Scientist, IICT-Hyderabad.

Awards:
INSPIRE Research fellowship from DST

Roshan Lal Makkar

PhD

Ihave a background of working in Bio medical Instrumentation area. I am a Scientist at SAMEER(Society for Applied Microwave Electronics Engineering & Research) since Dec 1998

Vaishali Pawar

PhD

I am B. pharm. (Government College of Pharmacy, Nasik), followed by M.S. (Pharm) from NIPER, Mohali, Punjab. My research area is Prevention and treatment of orthopaedic infections.

Anadi Gupta

M.Sc-PhD

I have completed my Graduation B.Sc in Biotechnology from C.S.J.M University Kanpur, M.Sc in biotechnology from IIT Bombay and Pursuing PhD in Biomedical Science From IIT Bombay. I am doing research work on NIR light sensitive films for microbial biofilm mediated disinfection and Transdermal Drug Delivery for orthopedic application.

Ashish Jha

M.Sc.-PhD

I did my B.Sc. from Rajasthan University and pursuing M.Sc.- PhD- Pursuing at IIT-B. My Research Area is working on Cancer treatment with photo thermal therapy I recewived 5 Month training at Elkon Pharmaceuticals, Jaipur (Rajasthan)

Mukesh Dhanka

M.Sc.-PhD

I had completed B.Sc in biotechnology from Rajasthan university in 2011.During my graduation I did two research project "Bear wine production by using Saccharomyces cerevisiae" in 2nd year and in 3rd "Effect of different anti-tubercular drug on TB patients".My hobbies include playing chess and reading novels. And in 2011 I got admission in IIT BOMBAY as M.Sc-PhD dual degree student. During M.Sc in NanoBios lab I started my research work on Drug delivery for bones and joints tuberculosis. I have been interested in drug delievry.The need of effective drug delivery system is increasing because it can provide good bioavailability, low toxicity, targeted and localized delivery of drug in controlled manner at the required site by using new smart bio-materials.

Arpan Pradhan

PhD

I am Arpan Pradhan, a new PhD student(2014) in NanoBios Lab. My area research involves thermosensitive drug delivery systems for cancer therapeutics. Before qualifying GATE 2011, I did my M.Tech (Biotechnology), 2013- Birla Institute of Technology, Mesra and B.Tech (Biotechnology), 2009- West Bengal University of Technology. Read More

I am Arpan Pradhan, a new PhD student(2014) in NanoBios Lab. My area research involves thermosensitive drug delivery systems for cancer therapeutics. Before qualifying GATE 2011, I did my M.Tech (Biotechnology), 2013- Birla Institute of Technology, Mesra and B.Tech (Biotechnology), 2009- West Bengal University of Technology.
Professional Experience:
INDIAN INSTITUTE OF TECHNOLOGY (IIT) Bombay, India Sept. 2013- May 2014 Research Assistant Supervisor: Dr. Rohit Srivastava (Department of Biosciences and Bioengineering) “TB NANODOTS: Transdermal controlled release of TB drugs”
BIRLA INSTITUTE OF TECHNOLOGY (BIT) MESRA, India July 2012- May 2013 M.Tech Project Supervisor: (Dr.) Manish Kumar (Department of Biotechnology) Co-supervisor: Prof. Kunal Mukhopadhyay (Department of Biotechnology) “Funtional Characterization and Process Parameter Optimization for High Recovery of Recombinant Gamma Synuclein”
INDIAN INSTITUTE OF TECHNOLOGY (IIT) Bombay, India July 2009- March 2011 Project Trainee Supervisor: Prof. Dhirendra Bahadur (Department of Metallurgical Engineering and Materials Science) “Thermo-responsive Poly(N-isopropylacrylamide)-Chitosan Based Magnetic Nanohydrogel for Drug Delivery Applications”
HALDIA INSTITUTE OF TECHNOLOGY (HIT) Haldia, India Sept. 2008- April 2009 B.Tech Project Supervisor: (Dr.) Siraj Dutta (School of Biotechnology & Life Sciences) “Enhancing Shelf Life of Fresh Betel Leaf for Long Distance Marketing”
INDIAN INSTITUTE OF TECHNOLOGY (IIT) Bombay, India June 2008- July 2008 Summer Trainee Supervisors: Prof. Dhirendra Bahadur (Department of Metallurgical Engineering and Materials Science) “Magnetic Nanoparticulates for Controlled and Targeted Drug Delivery”
JADAVPUR UNIVERSITY (JU) Kolkata, India July 2007- July 2007 Summer Trainee Supervisor: Prof. (Dr.) Pinaki Bhattacharya (Department of Chemical Engineering) “Isolation of Trypsin from Goat Pancreases using Affinity Ultrafiltration”

Syeda Aliya Sana

Research Associate

I am working as a Research Fellow in NanoBios Lab since August 2015. I completed my M Tech in Biotechnology from D.Y. Patil University. I am specialised in synthesis of semi-conductor quantum dots and their applications in disease diagnosis. I am also involved in development of Point-of-Care Multi-analyte sensing devices which are able to detect human serum electrolytes along with glucose and urea. In addition, I am also working on the development of biochemistry Kits for detection of serum electrolytes. Read More

Mukeshchand Thakur

Junior Research Fellow

Mukeshchand Thakur (M. Tech Biotechnology), previously IITB Research Internship Award Fellow 2014-2015 and is currently working as a Junior Research Fellow at Nanobios Lab. He is working in the field of 2D materials, quantum dots and plasmonic nanomaterials for nanoscale engineering, nanomedicine, biosensing, and photo-responsive applications. For further reading kindly visit: https://orcid.org/0000-0003-4561-595X Read More

Ashwini Dange

Senior Research Fellow

I have completed B.Pharmacy from Pune University and M.S.(Pharm) from NIPER, Kolkata in Medicinal Chemistry. I am proficient in Synthetic Organic Chemistry, Green Chemistry and Analytical Chemistry. Currently I am involved in the development of Point-of-care tests for different biological parameters. My expertise are development of chemistry for dipstick assays, lateral flow assays and its clinical validation. Read More

B. Pradeep Kumar Reddy

PhD

I, B. Pradeep Kumar Reddy have done Masters in Pharmaceutics from NIPER Mohali. I have 3 years industrial experience in nanoparticulate system (Liposomes and Nanoemulsion) system as well as conventional dosage forms. I am pursuing PhD with research focussed on Photothermal cancer therapy. Read More

Santosh Bodakhe

Project Staff

I completed Master’s degree from Department of Pharmaceutics, NIPER, S.A.S. Nagar, Punjab, India. I was a 2nd rank holder in all India NIPER Entrance exams with GATE 99.3% and B. Pharm from Pune University, India. I have 6 years of experience in national and multinational pharmaceutical organization. I have worked in various domain like formulation development, sterile liquid production, clinical research and regulatory. My NIPER research activities have made me part of PATENT and one RESEARCH PAPER which is accepted in Nanomedicine, one POSTER PRESENTATION which indicates my scientific caliber. Possess a keen interest in scientific research for improvement of health care services. Currently, I am working gold nanoparticles based lateral flow assay for HBA1C, colorimetric assay for cholesterol and triglyceride, alkaline phosphatase etc. Read More

Rajendra Prasad

Research Associate

Recently, I have joined as Research Associate at NanoBios, IIT-Bombay. I am currently working on functional nanomechine for targeted cancer theragnosis. I completed my Master of Science in 2010 from Chemistry Department, University of Kota. Later, I have decided to do something new in medical research and I entered into PhD at CSIR-NCL, Pune in Aug. 2011. I was taught the design of nanosized functional hybrids by my PhD guide Dr. Selvaraj at CSIR-NCL during my PhD (2011-2017). Multifunctional hybrid design is my specialization and now doing the fabrication of clinically relevant targeted nanomedicine with my current mentor Prof. Rohit at IIT-Bombay. We are also working for advanced localized cancer therapies viz., NIR light mediated photothermal therapy, combined photothermal-photodynamic therapy and multimodal diagnostics. Read More

Rohan Bahadur

Research Assistant

I completed my M.Sc Chemistry with specialization in Analytical chemistry. Currently I am working as a Junior Research fellow in Nanobios Lab since September 2016. My research interests are 2D materials such as graphene, MoS2, WS2, their hybrids and their 0D derivatives thereof for biomedical and sensor applications (heavy metal sensing, anti-counterfeiting materials, glucose sensing and electrochemical sensing). I am specialized in synthesis of fluorescent materials such as graphene quantum dots; MoS2 dots and their exfoliation techniques, etc. Read More

Vartika Verma

Research Assistant

I am Product Designer, working as Project Research Assistant at NanoBios Lab. I have completed my Bachelors of Design in Industrial Design from Symbiosis Institute of Design, Pune. Presently I am working on Water- less Sanitation System for Public Toilets in India and also working on projects which comprehend designing several medical devices. Read More

Pankaj Shivhare

PhD

I completed my B.Tech from ABES Engineering College, Uttar Pradesh Technical University, and M.S. by Research from National Institute of Technology Tiruchirappalli in Electronics & Instrumentation Engineering. I am currently pursuing Ph.D. under the supervision of Prof. Rohit Srivastava. My area of interest lies in the field of Bio-MEMS, Softlithography, and Electronics for healthcare devices. Currently, I am developing affordable point-of-care assays and colorimetric reader for quantitative measurement of albumin, creatinine, glycated albumin, cholesterol and triglyceride. Read More

Nikita Shriyan

Research Assistant

Early diagnosis of devastating disease is a must. Genetic analysis of cancer is restricted by the unavailability of molecular diagnostic kits at an individual level. Hence cancer is not detected at a very early stage.Presently here at NanoBios Lab I am finding solutions, for prognosis of various disorders. Molecular diagnostics with nanotechnology as a tool. After gaining research exposure as a research trainee I am currently working as a Research Assistant. I have completed my B.tech in Biotechnology from DY PATIL UNIVERSITY, 2016. I have been working on Micro-system In Drug Delivery Devices and also gained experience in Developing Bio-materials As Hemostatic Agent. Read More

Prabhu Raj

PhD

Myself, Prabhuraj R S completed my M.Tech Chemical Engineering in 2015 from Kongu Engineering College, Erode, Tamilnadu. I am hailing from Sivakasi (crackers city or small Japan of India). I joined Ph.D. in IIT Bombay, July 2015. My area of interest is Targeted nanoparticles and polymeric implant for drug delivery in pancreatic cancer. One can find more information about me on my personal website https://prabhuchemics1992.wixsite.com/prabhuraj Read More